Journal:

Article Title: In Vitro Activity of Trovafloxacin against Bacteroides fragilis in Mixed Culture with either Escherichia coli or a Vancomycin- Resistant Strain of Enterococcus faecium Determined by an Anaerobic Time-Kill Technique

doi: 10.1128/AAC.45.1.243-251.2001

Figure Lengend Snippet: In vitro activity of trovafloxacin against B. fragilis, E. coli , VREF, and E. faecium using different inocula with and without ACC

Article Snippet: The bactericidal activity of trovafloxacin was decreased in the presence of ACC as indicated by the 2- to 16-fold increase in the MBCs of all strains. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Inoculum (CFU/ml) ACC (mg/ml) Trovafloxacin activity (μg/ml) against: B. fragilis ATCC 23745 B. fragilis ATCC 25285 E. coli ATCC 25922 VREF BM4147 E. faecium SH17 MIC MBC MIC MBC MIC MBC MIC MBC MIC MBC 10 5 0.25 0.25 0.125 0.125 0.06 0.06 1 1 1 1 10 8 2 2 1 1 0.25 0.25 >64 >64 >64 >64 10 5 4 — a 2 — 1 — 1 — 8 — 8 10 8 4 — 4 — 2 — 4 — >64 — >64 Open in a separate window a —, MIC could not be read due to turbidity caused by ACC.

Techniques: In Vitro, Activity Assay

Journal:

Article Title: In Vitro Activity of Trovafloxacin against Bacteroides fragilis in Mixed Culture with either Escherichia coli or a Vancomycin- Resistant Strain of Enterococcus faecium Determined by an Anaerobic Time-Kill Technique

doi: 10.1128/AAC.45.1.243-251.2001

Figure Lengend Snippet: Reduction in bacterial counts of pure or mixed cultures of B. fragilis , VREF, E. faecium , or E. coli strains a

Article Snippet: The bactericidal activity of trovafloxacin was decreased in the presence of ACC as indicated by the 2- to 16-fold increase in the MBCs of all strains. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Inoculum (CFU/ml) ACC (mg/ml) Trovafloxacin activity (μg/ml) against: B. fragilis ATCC 23745 B. fragilis ATCC 25285 E. coli ATCC 25922 VREF BM4147 E. faecium SH17 MIC MBC MIC MBC MIC MBC MIC MBC MIC MBC 10 5 0.25 0.25 0.125 0.125 0.06 0.06 1 1 1 1 10 8 2 2 1 1 0.25 0.25 >64 >64 >64 >64 10 5 4 — a 2 — 1 — 1 — 8 — 8 10 8 4 — 4 — 2 — 4 — >64 — >64 Open in a separate window a —, MIC could not be read due to turbidity caused by ACC.

Techniques:

Journal: BMC Microbiology

Article Title: In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

doi: 10.1186/s12866-023-02886-x

Figure Lengend Snippet: Time-Kill Kinetics of WLBU2 and Colistin against P. aeruginosa. 1 A: concentration-dependent killing of P. aeruginosa ATCC27853 by WLBU2 and colistin; 1B: concentration-dependent killing of CRPA by WLBU2 and colistin. There was no significant difference in the killing activity between WLBU2 and colistin (P > 0.05). All data represent mean ± standard error of the mean (SEM) of 3 independent experiments

Article Snippet: According to the results, the MIC and MBC values of WLBU2 against MDR and ATCC 27,853 P. aeruginosa strains were 8 and 16 μg/mL, respectively, while both MIC and MBC against carbapenem resistant strain was 4 μg/mL.

Techniques: Concentration Assay, Activity Assay

Journal: BMC Microbiology

Article Title: In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

doi: 10.1186/s12866-023-02886-x

Figure Lengend Snippet: The effect of WLBU2 in different concentrations on dispersion of biofilm structure. MDR: Multidrug Resistant; CRPA: Carbapenem Resistant P. aeruginosa; SS: Standard Strain (ATCC 27,853)

Article Snippet: According to the results, the MIC and MBC values of WLBU2 against MDR and ATCC 27,853 P. aeruginosa strains were 8 and 16 μg/mL, respectively, while both MIC and MBC against carbapenem resistant strain was 4 μg/mL.

Techniques: Dispersion

Journal: BMC Microbiology

Article Title: In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

doi: 10.1186/s12866-023-02886-x

Figure Lengend Snippet: The expression levels of genes involved in P. aeruginosa biofilm formation influenced by WLBU2

Article Snippet: According to the results, the MIC and MBC values of WLBU2 against MDR and ATCC 27,853 P. aeruginosa strains were 8 and 16 μg/mL, respectively, while both MIC and MBC against carbapenem resistant strain was 4 μg/mL.

Techniques: Expressing